Wednesday Morning Oncology Journal Club

Wednesday Morning Oncology Journal Club

3455 321

7:30-8:30 AM

CHOMP 

Medical Staff Conference Room #1

                                             Dec 2025

Dec 3    ESR1 in Breast Cancer:  Imlunestrant

           “Imlunestrant with or without Abemaciclib in Advanced Breast Cancer”

                                     Jhaveri K, Neven P, Casalnuoco M, et al.  NEJM  March 27th, 2025

-Nancy Rubin

Dec 10   ESR1 in Breast Cancer:  Treat early or …. not ?

          “First Line Camizestrant for Emerging ESR1-Mutated Advanced Breast Cancer”

                                    Bidard F-C, Mayer E, Park YH et al. NEJM August 7th, 2025

-John Hausdorff

Dec 17   PROTAC:  Degradation is the new reality

          “Vepdegestrant, a PROTAC Estrogen Receptor Degrader in Advanced Breast Cancer”

                                    Campone M, De Laurentiis M., Komal Jhaveri, K et al. NEJM August 7th, 2025

              “Science behind the Study: Degradation of the Estrogen Receptor in Breast Cancer”

D.P. McDonnell.  NEJM August 7th, 2025

-Ron Garren

Dec 24    Holiday

Dec 31    Holiday